2013 > 06

Describe an approach to fish for specific autoreactive T cells and why you chose this method.

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What criterias does a disease have to fullfill to be considered an autoimmune disease? Why can it be difficult to to prove that a disease is of an autoimmune nature?
How can autoreactive T cells arise?

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 B cell tolerance is more difficult to achieve as compared to T cell tolerance. Why do you think that is the case? What mechanisms are in play?

 

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